1.history of the disease 2. definition and pathophysiology 3. epidemiology 4. diagnostic criteria and classification 5. clinical features 6. clinical assessment (history taking, mental state exam, physical examination, cognitive assessment , workup) workup includes blood, EEG, imaging. 7. differential diagnosis 8. risk factors 9. biomarkers 10. prevention and screening 11. management 12. prognosis 13. treatments in development