- Introduction (extensive literature review about:
- Thrombophilia or Hypercoagulability, to mention that Over-activity of coagulation factors is one of the most common causes of thrombophilia
- Factor VIII protein and FVIIIa's C2 domain binding to cell membrane property being possibly correlated to its activity, include these citations
a. Chavin, S. I., 1984
b. Shi, J. et al., 2004
c. Hsu, T. C., Pratt, K. P. & Thompson, 2008
d. Dalm, D et al. 2015 - Talk about Current ways to measure coagulation proteins activity i.e. the current ways to diagnose of Hemophilia A, vWD and Hypercoagulability