How have diseases affected the country over the centuries?

How have diseases affected the country over the centuries? choose a developing country to research.  You should not procrastinate on this as you might not find good sources of reference materials to use.  You are to choose one of the following topics: 1.    How have any major natural disasters within the last 100 years affected the country? 2.    How have diseases affected the country over the centuries? 3.    How have accidents affected the countries development and economy?