Hypothesis of depression and symptoms

  1. WG, a 31-year-old female, has been admitted to your inpatient unit from the ED where she presented unwillingly and accompanied by her husband. She is unable to provide a history right now, but her husband is able to give you the following information: He reports over the past 2 weeks the patient has been uncharacteristically energetic, starting tasks and not finishing them, exhibits hypersexuality, is highly distractible with speech that is "nonsensical". Her speech has also been rapid and pressured. She only sleeps every second or third night and has abdicated all attempts at self care such as hygiene or grooming. The ED diagnosed her with a manic episode. There is no documented history of smoking, alcohol, or illicit substance use. There is no history of any psychiatric illness in the patient or her family. A full work up has been completed and all was normal with the exception ofthe abnormal findings listed in the table below: LabNitals Today Blood pressure 150/90 (H) Sodium 123 (L) Provide recommendations for treatment (including diagnostic clarification, and focus on psychopharmacologic treatment) and monitoring for WG's current symptoms. 2. Describe and explain (neurobiologically) the monoamine hypothesis of depression and discuss the symptoms and circuits in mania.