Immune system

  I. Innate Immune System 1. MicroAssessment a. Describe the two sensor systems and three effector action of innate immunity. b. Describe granulocytes, which type of them is the most abundant and why? c. Why can bone marrow transplants be used to replace defective lymphocytes? d. What is inflammatory response; describe the two general events tha initiate the inflammation and two changes in cells undergoing apoptosis. 2. Applications: Patients who had recently a bone marrow transplant are very susceptible to infection. Why? Explain! II. Adaptive Immune System 1. MicroAssessment a. How is the cell-mediated response different from the humoral one? b. Why a person with AIDS be more susceptible to bacteria that cause tuberculosis? c. What mechanism do NK cells use to kill “self” cells? 2. Applications: What kind of diseases would be expected to happen (occur) as a result of lack of T and B lymphocytes?     III. Host-Microbe Interactions 1. MicroAssessment a. Give an example of microorganism(s) that cause a latent infection. b. Remember Koch’s postulates. How those postulates can be use to prove the cause of anthrax? c. Describe the three mechanisms pathogens may use to survive within phagocytic cells.