Mammalian DNA clustered regularly interspaced short palimdromic repeats

Does mammalian DNA have clustered regularly interspaced short palimdromic repeats? Can PCR be used in CRISPR Cas9? If yes, which step of the protocol can benefit from it? Where is Sanger sequencing used in CRISPR Cas9 based genome editing protocol? Does the data generated from this sequencing require bioinformatic tools for analysis? Explain what’s common between IVF, PGD and CRISPR Cas9 gene editing system?