The limitations of the systematic review

  Explain the importance of systematic review and meta-analysis for evidence-based practice. What are the limitations of the systematic review? How to overcome the challenges? Offer an example of a situation when a systematic review and meta-analysis were one of the defining points in the decision-making process, and when without it the decision might have been incorrect. https://training.cochrane.org/handbook http://www.ccace.ed.ac.uk/research/software-resources/systematic-reviews-and-meta-analyses https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/1471-2288-11-15 https://journals.sagepub.com/doi/pdf/10.1177/014107680309600304