The possibility of using CRISPR in combination with gene drives to reduce mosquito populations in areas with high rates of malaria transmission

Discuss the possibility of using CRISPR/Cas9 in combination with gene drives to reduce mosquito populations in areas with high rates of malaria transmission. Explain the CRISPR/Cas9 system as well as the concept of a gene drive. What is malaria and why is such a problem in certain parts of the world? What would be the pros and cons of introducing mosquitos engineered with a gene drive into wild populations?