Part I:
A primary care doctor consults with a married couple, male and female, both age 55. The male complains of being excessively fatigued, weak, depressed, is unable to lose weight and complains that he has lost his sex drive as well having some incidences of erectile dysfunction. He describes these symptoms as severe. After appropriate testing, the doctor’s diagnosis is low testosterone levels. The female indicates that she has ceased having menstrual periods for one year and complains of excessive hot flashes, night sweats that prevent her from getting a full night’s sleep, loss of sex drive, and increased anxiety and irritability. She also describes these symptoms as severe. After appropriate testing, the doctor’s diagnosis is menopause. If your birth year ends in an odd number, research and present a supported argument in favor of hormone replacement therapy for both individuals (testosterone in men, estrogens alone or in combination with progesterone in females). If your birth year ends in an even number, research and provide a supported argument against the use of hormone replacement therapy as indicated above for both individuals. Remember that all work is in your own words and sources must be valid and cited.
Part II:
Complete the online Karyotyping Activity at:
Karyotyping Activity. Report your results by listing the karyotype notation and diagnosis for Patients A, B and C.
Then answer the following questions.
How is karyotyping related to meiosis?
Which set of chromosomes appears to be most commonly involved in nondisjunction?
What types of genetic abnormalities would not be able to be identified via karyotyping?
Search the Internet for genetic abnormality other than those that you identified above for Patients A, B and C that could be identified through karyotyping. Identify the website and briefly report on the abnormality such as its rate of occurrence, effects and any potential treatments. Make sure to use your own words and provide correct citations.