1.The standard free energy of hydrolysis of inorganic polyphosphate (PPPPP) is about -20 kJ/mol for each Pi released. In a cell, it takes about 50 kJ/mol of energy to synthesize ATP from ADP and Pi. Is it feasible for a cell to use polyphosphate to synthesize ATP from ADP? Explain your answer.
2.Adults engaged in strenuous physical activity require an intake of about 160 g of carbohydrate daily but only about 20 mg of niacin (vit. B3) for optimal nutrition. Given the role of niacin in glycolysis, how do you explain the observation?