Required Practice: Epiville case-control modules http://epiville.ccnmtl.columbia.edu/modules.html Links to an external site. Required Reading: Christiaens I, Hegadoren K, Olson DM. 2015. Adverse childhood experiences are associated with spontaneous preterm birth: a case—control study. BMC Medicine 13(124) DOI 10.1186/s12916-015-0353-0.
(See attachement for article) Required Reading:
Christiaens I, Hegadoren K, Olson DM. 2015. Adverse childhood experiences are associated with spontaneous preterm birth: a case—control study. BMC Medicine 13(124) DOI 10.1186/s12916-015-0353-0.
Assigned Questions:
1.What was the purpose of the study? 2.What was the main exposure in broad terms? Hint: how would you summarize the types of items on the Wellbeing and Pregnancy Questionnaire described in the Methods section? 3.What was the main outcome? 4.How were cases defined (1 sentence)? 5.How were controls defined (1 sentence)? 6.Do you think an appropriate control group was used? Why or why not? Hint: Read the second to last line in the Study Participants section. 7.Refer to Table 1 and the column that says “Crude OR.” What does the OR for Higher ACE Score (?2) mean? The reference group is described in the Univariate Analysis section of the Results. 8.The authors tell us that 75 cases and 148 controls completed the Wellbeing and Pregnancy questionnaire. Calculate the OR between high stress compared to low stress assuming that 45 of the cases and 66 of the controls reported high stress.
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