– What is hedgehog signalling? (Describe every detail starting from types of ligands, receptor(s), how it’s activated, how it’s inactivated, downstream
processes until gene expression)
– How it can induce osteogenesis in mesenchymal stem cells?
– what are the gene markers? Transcriiption factors? Proteins markers?
– any agonists? Antagonists? Bone diseases associated?
Same points should be explained for the following signalling pathways: