Spermatogonial stem cells (SSCs) produce sperm throughout the

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Spermatogonial stem cells (SSCs) produce sperm throughout the

post-pubertal life ofa male. The self-renewal and differentiation ofthese cells is controlled by glial-cell-line-derived neurotrophic
factor (GDNF). Discuss the role of GDNF signalling in the maintenance and differentiation of SSCs.

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